Collecting this in one place because it comes up every few weeks and the answer is always assembled from scratch. It is about vendor vetting, and it is deliberately narrow — everything I am not confident about is marked as such.
What is actually established
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion. Synthesis, testing, and cold-chain shipping have floors. A price well under the floor means something was skipped, and the two things that get skipped are testing and content.
The condition it depends on
One flattering data point from a group buy is not consistency. Consistency means separate batches, separately commissioned, over months.
The practical version
Red flags, in rough order of how much they should worry you: no verifiable address, no batch numbers, prices far under market, vendor-commissioned tests only, pressure toward irreversible payment, and shipping with no temperature control.
What I am not sure about
What I am trying to establish is how people are distinguishing a supplier having a bad batch from a supplier on the way out. I would rather have one careful answer than five confident ones.
— amsterdam_pete · corrections welcome and will be edited into this post with credit