dave_SLC said:

I did not do what was suggested, I did something adjacent, and it worked; posting the difference in case it matters to somebody.

This answered a question I did not know how to ask. Taking it to my next appointment.

From the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

TrialNerd_Beth said:

Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.

TrialNerd_Beth said:

Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Adding the part of the answer the thread has not reached. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.