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ForumsNutrition & SupplementationIron deficiency on GLP-1 — May 2025

Iron deficiency on GLP-1 — May 2025

tony_orlando Tue, May 6, 2025 at 1:18 AM 6 replies 1,405 viewsPage 1 of 2
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tony_orlando
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Orlando, FL
May 6, 2025 at 1:18 AM#1

I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

What I actually want to know is which deficiencies actually show up when intake drops this far, and which are worth testing rather than supplementing blind.

Practical detail welcome, however dull — the duller the better.

21 16NauseaFreeNow, SteveThurs, B12Beth and 18 others
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DataDave
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May 6, 2025 at 2:53 AM#2
tony_orlando said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 88 → 98 fL. This flagged potential B12 or folate deficiency.

Sure enough, B12 had dropped from 620 to 340 pg/mL. Started B12 injections monthly and MCV normalized within 2 months. GLP-1 agonists can impair B12 absorption — this is a real clinical concern that deserves routine monitoring.

20 15mike_nyc, VendorMark, COA_Karl and 17 others
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fiona_VT
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May 6, 2025 at 4:28 AM#3
DataDave said:
Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 88 → 98 fL.

Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly:

  • B12: Can drop due to reduced GI absorption. Mine went from 650 to 380 — now supplementing.
  • Iron/Ferritin: Reduced food intake = reduced iron. Ferritin dropped from 66 to 23. Supplementing.
  • Vitamin D: Was already low (21 ng/mL), now taking 5000 IU daily.
  • Folate: Stable, no issues.
  • Zinc: Slightly low, added a multivitamin with zinc.

Nutritional deficiencies are a real risk when you're eating significantly less. Don't skip your labs!

Last edited: May 6, 2025 at 5:28 AM
19 14jason_sac26, chris_chi24, tampaLisa73 and 16 others
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tom_AK
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Anchorage, AK
May 6, 2025 at 6:03 AM#4
tony_orlando said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Adding a me-too, because a thread of one person's experience is not much use.

18 13jennifer_SEA, tyler_CSCS, VanRx_Mike and 15 others
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Dr.LipidDallas
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May 6, 2025 at 3:22 PM#5

Adding the clinical framing, because it changes how the question reads.

Iron studies on micronutrients — important especially for women:

MarkerBaselineMonth 6After Supplementation
Ferritin572047
Iron875280
TIBC312382332
Transferrin Sat34%17%27%

My ferritin cratered at month 6 from reduced dietary intake. Iron bisglycinate 36mg with vitamin C brought it back up. Don't wait for anemia symptoms — test proactively.

17 12Dr.PulmRoch, maya_sedona, stefan_berlin and 14 others
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