TrialTracker_MD said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

No disagreement with TrialTracker_MD. One condition attached. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

That is the short version; the long version is somebody else's post.

Dr.PulmRoch said:

Agreed, with a caveat about community reputation: it is a lagging indicator.

Bookmarking. The distinction being drawn above is the one nobody else makes.

TrialTracker_MD said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Pushing back on TrialTracker_MD here. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Happy to go further on any of that.

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Tagging this one for the weekly digest.