Dr.PeteFamMed said:

On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

Adding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

BenResearch_OR said:

I will push back on the powder-first advice.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

One thing that is still open after LondonLisa’s answer:

Whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be?

Reporting back.

Front-loading was the answer. Same total intake, same drug, but two thirds of the protein before midday and I am hitting the target most days now.