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ForumsNutrition & SupplementationProtein requirements on GLP-1: systematic review of RDA vs optimal intake — anyone have experience? Page 3

Protein requirements on GLP-1: systematic review of RDA vs optimal intake — anyone have experience?

tammy_FL Sun, Oct 6, 2024 at 7:18 AM 15 replies 1,875 viewsPage 3 of 3
quinn_sf
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Oct 7, 2024 at 12:57 AM#11
lisa_labSD said:
The RDA is the wrong reference and it is worth understanding why.

That reframing is the part I needed. I will report back once I have actually tried it.

40 13tane_welly, Dr.PathRoch, mona_PHX and 37 others
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BariatricNurseD
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Oct 7, 2024 at 3:26 AM#12

Clinical perspective, offered as context rather than as advice.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass250 lbs220 lbs207 lbs
Fat mass110 lbs70 lbs42 lbs
Lean mass148 lbs153 lbs154 lbs
Body fat %43%33%21%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.4g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

Last edited: Oct 7, 2024 at 8:26 AM
41 14roxy_nash, tony_orlando, Dr.NephBHM_UK and 38 others
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Dr.GastroMayo
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Oct 7, 2024 at 5:55 AM#13
TrialTracker_MD said:
The gap between trial results and real-world results is consistent and it is not fraud.

This is where I part company with the consensus forming above. I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.

42 15COA_Karl, MikeFit_NJ, InsuranceTom and 39 others
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dave_SLC
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Oct 7, 2024 at 8:24 AM#14

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Worth separating that from the trial evidence, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: Oct 7, 2024 at 12:24 PM
43 16FranDenver, Dr.BariatricHTX, LindaRN_retired and 40 others
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mike_mod
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Oct 7, 2024 at 10:53 AM#15

Moderator note: a couple of off-topic posts removed. Thread quality here is what the rules are for. Keep it up.

44 17PurityPaulOR, MaxMetOK, MounjBrad and 41 others
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