Dr.PulmRoch said:If you are going to change something, change one thing and give it long enough to express itself.
This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.
Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
TrialTracker_MD said:Start from the measurement rather than the conclusion.
Second this. Posting only so the count is not one.
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Browse GL BiochemTrialTracker_MD said:Start from the measurement rather than the conclusion.
Adding the part of the answer the thread has not reached. The trials generally allowed a step to be held or reduced and then retried, and people who did that mostly arrived at the same place a few weeks later. The end point of the ladder is set by tolerability, not by a schedule, and there is no evidence that reaching the top faster produces a better outcome.
Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.