pete_nash said:

The version of this that has an answer is narrower than the version being asked.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

tom_AK said:

Right, and one flattering data point from a group buy is not consistency.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

pete_nash said:

The version of this that has an answer is narrower than the version being asked.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.