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ForumsDosing & ProtocolsTirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide Page 20

Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

Dr.Martinez Mon, Feb 19, 2024 at 5:20 PM 181 replies 34,127 viewsPage 20 of 20
kate.chem
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Aug 3, 2024 at 5:27 PM#96
anders_CPH said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

36 11steve_okc, dave_SLC, FDA_TrackerJim and 33 others
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NurseLeah_Nash
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Aug 5, 2024 at 5:32 PM#97
anders_CPH said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

35 10BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 32 others
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Dr.Martinez
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Aug 7, 2024 at 5:36 PM#98

Reporting back.

Update — I came back down one step, held for a month, then went up again and it was uneventful the second time. Same ladder, slower.

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EndoResFellow
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Aug 9, 2024 at 5:38 PM#99

Worth restating a point from upthread for anyone joining at this page:

True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of people never reach the dose the headline number came from.

Last edited: Aug 9, 2024 at 7:38 PM
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steve_okc
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Aug 11, 2024 at 5:39 PM#100
EndoResFellow said:
True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of…

Can confirm. Same sequence, different timescale.

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