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ForumsDosing & ProtocolsWeekend vs weekday injection — does timing of dose day matter? Page 3

Weekend vs weekday injection — does timing of dose day matter?

matt_MKE Sat, May 23, 2026 at 11:12 PM 11 replies 508 viewsPage 3 of 3
Dr.LipidDallas
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May 31, 2026 at 9:11 AM#11
Dr.SportsMedIN said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

Last edited: May 31, 2026 at 11:11 AM
18 16pam_stl, wei_SG, cory_ATX and 15 others
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SkepticalSean
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Jun 1, 2026 at 9:47 PM#12
SkepticalSean said:
That is right for the weekly injectables.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Adding it to my notes with a link back to this thread.

19 17paige_pharma, emma_london, tammy_FL and 16 others
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Dr.BariatricHTX
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Jun 3, 2026 at 10:22 AM#13
Dr.SportsMedIN said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

Last edited: Jun 3, 2026 at 4:22 PM
20 18Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 17 others
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Dr.NateNeph
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Jun 4, 2026 at 10:57 PM#14

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

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mike_mod
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Jun 6, 2026 at 11:31 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

22 20PurityPaulOR, MaxMetOK, MounjBrad and 19 others
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