Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Dr.NephBHM_UK said:The mechanism and the magnitude are separate questions.
Adding a me-too, because a thread of one person's experience is not much use. The detail I would add is minor and it is already implied above.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsDr.NephBHM_UK said:The mechanism and the magnitude are separate questions.
There is a second half to this that has not been said yet. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.