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Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsNeedle length selection — anyone have experience? Page 5

Needle length selection — anyone have experience?

fiona_VT Tue, Feb 24, 2026 at 2:11 AM 36 replies 1,655 viewsPage 5 of 8
Dr.PathRoch
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Mar 10, 2026 at 3:47 AM#21

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: Mar 10, 2026 at 9:47 AM
5 3MikeFit_NJ, InsuranceTom, WendyG_ATL and 2 others
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SallyK_inj
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Mar 14, 2026 at 12:46 PM#22

Following on from Dr.LeslieOBGYN — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

Last edited: Mar 14, 2026 at 1:46 PM
6 4bbq_ray_KC, oliver_london, tane_welly and 3 others
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nick_SD_fit
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Mar 18, 2026 at 9:43 PM#23
Dr.PathRoch said:
If you are going to change something, change one thing and give it long enough to express itself.

Pushing back on Dr.PathRoch here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

7 5EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 4 others
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pete_nash
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Mar 23, 2026 at 6:37 AM#24
Dr.PathRoch said:
If you are going to change something, change one thing and give it long enough to express itself.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

8 6SarahChen_PharmD, sarah.morrison, NeuroNate and 5 others
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carlos_SATX
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San Antonio, TX
Mar 27, 2026 at 3:29 PM#25
Dr.PathRoch said:
If you are going to change something, change one thing and give it long enough to express itself.

This is exactly what I could not find anywhere else.

9 7tommy_boulder, hyun_seoul, jim_asheville and 6 others
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