BariatricNurseD said:I want to add the drug interaction perspective on the pharmacology.
That reframing is the part I needed. Adding it to my notes with a link back to this thread.
Adding the clinical framing, because it changes how the question reads. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.
Ask again with the specifics and you will get a better answer than this one.
SleepDoc_PDX said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
I read this differently from SleepDoc_PDX, on substance rather than tone. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.
Ask again with the specifics and you will get a better answer than this one.
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Browse GL BiochemThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.