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ForumsDosing & ProtocolsInjection bruise the size of a quarter - normal?? — my results so far Page 3

Injection bruise the size of a quarter - normal?? — my results so far

sarah_nash92 Tue, Nov 25, 2025 at 10:32 AM 15 replies 1,263 viewsPage 3 of 3
Dr.MetabolicMD
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Nov 28, 2025 at 5:18 PM#11
Dr.ReproEndo said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

40 15SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 37 others
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marco_milano
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Nov 28, 2025 at 8:32 PM#12
DadBodDave said:
Agreed on the arithmetic, with one condition: holding indefinitely at a dose that is not doing anything is not patience, it is a stall with a nice…

This is exactly what I could not find anywhere else.

39 14alex_tucson, kevin_tulsa, Dr.PainCLE and 36 others
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TomFromTexas
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Nov 28, 2025 at 11:46 PM#13
Dr.ReproEndo said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

I read this differently from Dr.ReproEndo, on substance rather than tone. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

Last edited: Nov 29, 2025 at 1:46 AM
38 13Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 35 others
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Dr.RaviCardio
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Nov 29, 2025 at 3:00 AM#14

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

37 12hans_munich, jason_sac26, chris_chi24 and 34 others
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mike_mod
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Nov 29, 2025 at 6:14 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

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