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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesPost-prandial glucose control — GLP-1 vs DPP-4 vs SGLT2i comparison Page 3

Post-prandial glucose control — GLP-1 vs DPP-4 vs SGLT2i comparison

SarahChen_PharmD Thu, May 28, 2026 at 8:19 PM 21 replies 573 viewsPage 3 of 5
A1cHero_PHX
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May 30, 2026 at 2:06 PM#11
Dr.MetabolicMD said:
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction…

Genuinely useful, thank you. I had the facts and not the framework.

31 6zoe_NC, Dr.ObesityLA, NurseKim_ATL and 28 others
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newstart_MO
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May 30, 2026 at 10:20 PM#12

From the other side of the consultation, briefly. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Correct me if the detail matters more than I have assumed.

Last edited: May 31, 2026 at 4:20 AM
30 5LibrarianMeg, bri_stats, pete_manc_UK and 27 others
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DanielChem_CHI
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May 31, 2026 at 6:33 AM#13
hyun_seoul said:
Patient selection optimization for glycaemic control: emerging predictive biomarkers for GLP-1 agonist response include: Biomarker Association…

This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Last edited: May 31, 2026 at 8:33 AM
29 4patPC_UT, Dr.DermMIA, fiona_VT and 26 others
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LabKate
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May 31, 2026 at 2:47 PM#14

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

28 3emily_PDX, Dr.SleepRoch, laura_annarbor and 25 others
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mike_mod
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May 31, 2026 at 11:01 PM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.

27 2PurityPaulOR, MaxMetOK, MounjBrad and 24 others
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