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ForumsBuyer Beware⚠ Counterfeit Ozempic pens circulating — my results so far Page 2

⚠ Counterfeit Ozempic pens circulating — my results so far

TrialTracker_MD Mon, Nov 3, 2025 at 12:00 PM 11 replies 1,203 viewsPage 2 of 3
Dr.AddMedPHL
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Nov 3, 2025 at 2:12 PM#6

The figures, for anyone assembling their own picture. For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and subcutaneous bioavailability near 89%. Those four numbers explain most of the questions people ask about timing.

16 11FitDadDave, RunnerRach, TrialNerd_Beth and 13 others
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hans_munich
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Jul 2024
Munich, DE
Nov 3, 2025 at 3:03 PM#7

A narrower follow-up, since the general answer is now clear:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

15 10alex_tucson, kevin_tulsa, Dr.PainCLE and 12 others
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pete_nash
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Nashville, TN
Nov 3, 2025 at 3:54 PM#8
Dr.AddMedPHL said:
For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

Coming at Dr.AddMedPHL’s question from a different direction. The dose-response is real but shallow at the top. Across STEP 1 and STEP 4 the gap between 1.7mg and 2.4mg is a couple of percentage points of body weight on average, and the average is carrying a wide spread — plenty of people at 1.7mg sit above the 2.4mg mean. If a dose is working and tolerable, "working" is the relevant variable, not "maximal".

14 9mike_mod, SarahChen_PharmD, sarah.morrison and 11 others
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TrialTracker_MD
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Jan 2024
Maryland
Nov 3, 2025 at 4:45 PM#9

Closing the loop on my own question.

Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.

Last edited: Nov 3, 2025 at 9:45 PM
13 8Dr.PulmRoch, maya_sedona, stefan_berlin and 10 others
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A1cHero_PHX
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Phoenix, AZ
Nov 3, 2025 at 8:52 PM#10
pete_nash said:
The dose-response is real but shallow at the top.

No disagreement with pete_nash. One condition attached. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.

Ask again with the specifics and you will get a better answer than this one.

1 1jason_sac26
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