VanRx_Mike said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
greg_boulder said:The pharmacokinetics explain nearly every practical question asked here.
Thank you for spelling out the reasoning rather than just the conclusion.
VanRx_Mike said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
I read this differently from VanRx_Mike, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
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Browse GL BiochemAdding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.