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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsHas anyone dealt with receptor internalization and recycling? Page 5

Has anyone dealt with receptor internalization and recycling?

steph_laguna Tue, Nov 11, 2025 at 8:29 AM 28 replies 1,190 viewsPage 5 of 6
chris_chi24
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Sep 2024
Chicago, IL
Nov 15, 2025 at 2:14 AM#21
hank_denver said:
Worth stating the units and the reference range whenever you post a number here.

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

Last edited: Nov 15, 2025 at 5:14 AM
20 18nick_newbie, DadBodDave, AmyNC_wife and 17 others
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sarah_TO
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Toronto, CA
Nov 15, 2025 at 9:44 AM#22
hank_denver said:
Worth stating the units and the reference range whenever you post a number here.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

21 19Dr.EndoEP, GraceAZ_72, carl_compliance and 18 others
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Dr.SportsMedIN
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Nov 15, 2025 at 5:14 PM#23

Adding the clinical framing, because it changes how the question reads. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: Nov 15, 2025 at 10:14 PM
22 20adam_van, Dr.SurgeonPGH, rachel_ABQ and 19 others
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SkepticalSean
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Nov 16, 2025 at 12:44 AM#24
Dr.SportsMedIN said:
The useful move here is to separate what is established from what is widely repeated.

Can confirm. Same sequence, different timescale. Nothing to add that would improve it.

23 21tammy_FL, Dr.LipidDallas, alex_tucson and 20 others
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BrianDallas92
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Oct 2024
Dallas, TX
Nov 16, 2025 at 8:14 AM#25
Dr.SportsMedIN said:
The useful move here is to separate what is established from what is widely repeated.

There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Nov 16, 2025 at 9:14 AM
24 22GraceAZ_72, carl_compliance, DanielChem_CHI and 21 others
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