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ForumsDosing & ProtocolsAir bubbles in syringe — 12 month update Page 4

Air bubbles in syringe — 12 month update

fiona_glasgow Wed, Sep 11, 2024 at 12:21 PM 48 replies 2,979 viewsPage 4 of 10
Dr.EM_Chicago
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May 2024
Chicago, IL
Sep 19, 2024 at 12:59 PM#16

Clinical perspective, offered as context rather than as advice.

dosing arithmetic — critical reminder about tirzepatide dose equivalence across formulations:

Mounjaro KwikPen and compounded tirzepatide are the same molecule but:

  • KwikPen is ready to inject, no mixing needed
  • Compounded requires reconstitution and proper syringe technique
  • Verify your compounded concentration before each injection
  • Never assume 1 vial = 1 dose without checking the math
30 3jim_asheville, matt_MKE, Dr.ReproEndo and 27 others
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tane_welly
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Sep 2024
Wellington, NZ
Sep 20, 2024 at 8:17 PM#17
Dr.GutHealth said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Sharing my dosing arithmetic titration experience with compounded semaglutide — I have been tracking injection volumes meticulously:

Using 5mg/2mL concentration with 1cc insulin syringes:

  • Month 1: 10 units (0.25mg) — mild appetite reduction
  • Month 2: 20 units (0.5mg) — significant appetite suppression
  • Month 3: 30 units (0.75mg) — custom intermediate dose
  • Month 4: 40 units (1.0mg) — optimal for me, staying here

The beauty of compounded vials is you can do custom intermediate doses. My provider was great about tailoring to my response.

31 4carl_compliance, DanielChem_CHI, marco_milano and 28 others
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DeniseRN_TPA
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Aug 2024
Tampa, FL
Sep 22, 2024 at 3:36 AM#18
Dr.GutHealth said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Bookmarking. The distinction being drawn above is the one nobody else makes. Taking it to my next appointment.

Last edited: Sep 22, 2024 at 6:36 AM
32 5tommy_boulder, hyun_seoul, jim_asheville and 29 others
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Dr.MetabolicMD
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Rochester, MN
Sep 23, 2024 at 10:56 AM#19

From the other side of the consultation, briefly.

Bacteriostatic water quality matters for dosing arithmetic reconstitution. Not all BAC water is created equal:

  • Should contain 0.9% benzyl alcohol as preservative
  • Must be sterile and pyrogen-free
  • Should come in a sealed, intact vial
  • Check expiration date — yes, BAC water expires
  • Store at room temperature, protected from light

I buy from a reputable medical supply company, not Amazon marketplace sellers. The $3 savings isn't worth the infection risk from unverified BAC water.

33 6Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 30 others
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Admin
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Sep 24, 2024 at 6:16 PM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.

5 3PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 2 others
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