🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesHOMA-IR tracking on GLP-1 — looking for input Page 9

HOMA-IR tracking on GLP-1 — looking for input

FDA_TrackerJim Tue, Nov 18, 2025 at 8:10 PM 41 replies 1,975 viewsPage 9 of 9
MariaRD
Member
823
4,567
Jun 2024
New Mexico
Apr 26, 2026 at 3:44 AM#41
traveltech_sara said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

5 3Dr.NutriCornell, pam_stl, wei_SG and 2 others
Reply Quote Save Share Report
DoseLogDan
Member
201
567
Feb 2025
Montana
May 3, 2026 at 1:52 AM#42
traveltech_sara said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Adding the part of the answer the thread has not reached. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

6 4Dr.AddMedPHL, newstart_MO, mia_MS2 and 3 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
May 9, 2026 at 11:55 PM#43

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.

7 5DoseLogDan, SleepFixSam, PurityPaulOR and 4 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
pete_nash
Member
312
1,345
Aug 2024
Nashville, TN
May 16, 2026 at 9:55 PM#44

Following on from traveltech_sara — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

8 6SarahChen_PharmD, sarah.morrison, NeuroNate and 5 others
Reply Quote Save Share Report
TrialNerd_Beth
Senior Member
2,345
11,234
Jan 2024
Bethesda, MD
May 23, 2026 at 7:51 PM#45
DoseLogDan said:
It is worth asking what the claim would look like if it were false.

This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

Last edited: May 23, 2026 at 11:51 PM
9 7SleepFixSam, PurityPaulOR, MaxMetOK and 6 others
Reply Quote Save Share Report
1789

Similar Threads

SUSTAIN-6 to SELECT — the cardiovascular evidence timeline14 replies
GLP-1 and insulin resistance — HOMA-IR improvement data17 replies
Metabolic syndrome reversal criteria — how GLP-1 addresses all 55 replies
A1C target achievement rates — sema vs tirz comparison8 replies
SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register