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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsReceptor internalization and recycling — anyone have experience? Page 8

Receptor internalization and recycling — anyone have experience?

jennifer_SEA Sat, Apr 26, 2025 at 6:12 AM 36 replies 2,034 viewsPage 8 of 8
Dr.RheumBOS
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May 15, 2025 at 8:12 PM#36
lucas_SP_BR said:
One practical note: write down what you did and when, before you need it.

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: May 16, 2025 at 2:12 AM
23 21pam_stl, wei_SG, cory_ATX and 20 others
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
May 16, 2025 at 9:35 PM#37
lucas_SP_BR said:
One practical note: write down what you did and when, before you need it.

This answered a question I did not know how to ask.

24 22hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 21 others
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traveltech_sara
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May 17, 2025 at 10:57 PM#38

Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

25 23wanda_boise, NurseAsh_DET, BenResearch_OR and 22 others
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amy_econ_NJ
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May 19, 2025 at 12:19 AM#39
traveltech_sara said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Adding a me-too, because a thread of one person's experience is not much use. The detail I would add is minor and it is already implied above.

Last edited: May 19, 2025 at 3:19 AM
26 24gary_naperville, sean_dublin, hannah_MT and 23 others
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MikeFit_NJ
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May 20, 2025 at 1:40 AM#40
traveltech_sara said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: May 20, 2025 at 4:40 AM
48 21Dr.EndoIndy, tom_AK, josh_phd_bmore and 45 others
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