PharmacoVig_BOS said:

Keep the original post as written when you update it, and add the correction underneath.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

Ask again with the specifics and you will get a better answer than this one.

PharmacoVig_BOS said:

Keep the original post as written when you update it, and add the correction underneath.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

Adding the clinical framing, because it changes how the question reads. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

hyun_seoul said:

The useful move here is to separate what is established from what is widely repeated.

This matches mine closely enough to be worth saying so out loud.

Closing the loop on my own question.

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect. Two curves, and I had been watching the wrong one.