Dr.NateNeph said:I want to add the drug interaction perspective on the pharmacology.
This answered a question I did not know how to ask.
Clinical perspective, offered as context rather than as advice. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.
Dr.CardioMD said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Pushing back on Dr.CardioMD here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.
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Browse GL BiochemOne concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.