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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsWait so orforglipron means no injection AND no fasting? Sign me up — anyone have experience? Page 3

Wait so orforglipron means no injection AND no fasting? Sign me up — anyone have experience?

VanRx_Mike Sat, Jan 10, 2026 at 1:19 PM 34 replies 1,190 viewsPage 3 of 7
BenResearch_OR
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Jan 12, 2026 at 3:11 PM#11
Dr.PeteFamMed said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

10 10julia.endo, JessicaM_2024, TomFromTexas and 7 others
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fiona_glasgow
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Jan 14, 2026 at 9:48 AM#12
Dr.LipidDallas said:
The manufacturing argument is the underrated one.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

9 9TirzTom, TrialTracker_MD, JennaRN and 6 others
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tammy_FL
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Jan 16, 2026 at 4:27 AM#13
Dr.PeteFamMed said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

I read this differently from Dr.PeteFamMed, on substance rather than tone. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

8 8kevin_tulsa, Dr.PainCLE, mike_mealprep and 5 others
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stefan_berlin
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Jan 17, 2026 at 11:07 PM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

I would rather be corrected than agreed with, if it comes to it.

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mike_mod
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Jan 19, 2026 at 5:47 PM#15

Moderator note: a couple of off-topic posts removed.

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