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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralSupport group thread — for those struggling with side effects and doubt

Support group thread — for those struggling with side effects and doubt

NurseLeah_Nash Sat, May 30, 2026 at 10:44 AM 20 replies 740 viewsPage 1 of 4
NurseLeah_Nash
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Sep 2024
Nashville, TN
May 30, 2026 at 10:44 AM#1

The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

The narrow version of the question is how people separated a drug effect from the ordinary consequences of a large deficit and disrupted sleep, because I cannot.

If the honest answer is that nobody knows, that is a useful answer and I would rather have it.

16 11RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 13 others
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COA_Karl
Senior Member
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Jan 2024
Pennsylvania
May 30, 2026 at 11:10 AM#2
NurseLeah_Nash said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.
NurseLeah_Nash said:
...mental health should only be used alongside therapy...

I'd say therapy should be AVAILABLE to all GLP-1 patients, but requiring it as a precondition for treatment would create an access barrier.

Not everyone can afford therapy. Not everyone needs it. Some people do just fine with medication + lifestyle changes. But for those with emotional eating, body image issues, or disordered eating history, therapy is extremely valuable.

My recommendation: make mental health screening part of the initial assessment, offer therapy as a recommended adjunct, but don't gatekeep medication access behind it.

15 10jim_asheville, matt_MKE, Dr.ReproEndo and 12 others
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maya_sedona
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Sep 2024
Sedona, AZ
May 30, 2026 at 11:37 AM#3
COA_Karl said:
NurseLeah_Nash said: ...mental health should only be used alongside therapy...

Recovering from an eating disorder and using mental health: this is a complex situation and I want to be transparent about it.

I have a history of binge eating disorder. My psychiatrist, therapist, and prescribing doctor all collaborate on my care. The GLP-1 agonist has actually been therapeutic — it removes the biological urgency of binge impulses without relying on restriction.

This is NOT appropriate for all ED patients. Anorexia, bulimia, and restrictive EDs require different approaches. But for BED specifically, the evidence and my personal experience are positive. Always involve your mental health team.

14 9BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 11 others
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hannah_MT
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Feb 2026
Bozeman, MT
May 30, 2026 at 12:03 PM#4
NurseLeah_Nash said:
The weight came off and the harder part started, which is not what any of the material I read had prepared me for.

Same experience, arrived at from the opposite direction.

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Dr.AddMedPHL
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Mar 2024
Philadelphia, PA
May 30, 2026 at 2:27 PM#5

From the other side of the consultation, briefly.

When to call your doctor about mental health side effects — a reference I wish I'd had:

Call immediately:

  • Severe abdominal pain (could be pancreatitis)
  • Vision changes (thyroid concern)
  • Lump in neck (thyroid nodule)
  • Severe vomiting/can't keep fluids down for 24h+

Schedule an appointment:

  • Persistent nausea beyond 4 weeks
  • Significant hair loss
  • Mood changes or depression
  • Gallbladder symptoms (RUQ pain after eating)
12 7JessicaM_2024, TomFromTexas, mike.trainer_LA and 9 others
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