Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
LabKate said:Keep the original post as written when you update it, and add the correction underneath.
Coming at LabKate’s question from a different direction. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.
The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
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Browse GL BiochemA narrower follow-up, since the general answer is now clear:
What would you measure differently if you were starting again?
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