Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

PeptideChemSF said:

Keep the original post as written when you update it, and add the correction underneath.

There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

One thing that is still open after PeptideChemSF’s answer:

What would you measure differently if you were starting again?

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.