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ForumsOral GLP-1 AgonistsHas anyone dealt with oral glp-1 adherence? Page 2

Has anyone dealt with oral glp-1 adherence?

sarah.morrison Wed, Sep 10, 2025 at 6:42 PM 33 replies 1,760 viewsPage 2 of 7
PharmacoVig_BOS
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Sep 10, 2025 at 7:58 PM#6

Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Sep 10, 2025 at 10:58 PM
26 21amsterdam_pete, LondonLisa, mike_nyc and 23 others
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dan_philly
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Sep 10, 2025 at 8:27 PM#7

One thing that is still open after sean_dublin’s answer:

How much of the oral variability is the SNAC absorption window and how much is dose, because the two get conflated constantly?

Last edited: Sep 10, 2025 at 11:27 PM
25 20AmyNC_wife, SkepticalSean, Dr.CardioMD and 22 others
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ingrid_STO
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Sep 10, 2025 at 8:56 PM#8
PharmacoVig_BOS said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Adding the part of the answer the thread has not reached. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

24 19MikeFit_NJ, InsuranceTom, WendyG_ATL and 21 others
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sarah.morrison
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Sep 10, 2025 at 9:25 PM#9

Reporting back.

Update — I went back to the injectable. Not because the tablet did not work, but because the fasting window and my mornings were never going to agree.

23 18Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 20 others
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Dr.RenalNash
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Sep 10, 2025 at 11:44 PM#10
ingrid_STO said:
It helps to say which part of this you are uncertain about.

ingrid_STO has the substance of this right. The condition it depends on is worth stating. Worth adding that the tablet is taken daily, so a missed dose costs far less than a missed weekly injection. That is a genuine advantage nobody lists.

That is the short version; the long version is somebody else's post.

Last edited: Sep 11, 2025 at 4:44 AM
37 12maria_elpaso, anders_CPH, Dr.NutriCornell and 34 others
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