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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsCost projections for oral non-peptide GLP-1 agonists — need advice Page 2

Cost projections for oral non-peptide GLP-1 agonists — need advice

VendorMark Mon, Aug 25, 2025 at 2:08 AM 12 replies 1,301 viewsPage 2 of 3
PharmD_Rodriguez
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Aug 25, 2025 at 5:14 AM#6
mike_nyc said:
Denials are usually procedural rather than clinical, and the order that works reflects that.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Small molecule does not automatically mean cheap. Price is set by what the market will bear and by patent life, not by cost of goods, and I would not assume the savings reach patients.

50 20paul_denver, TinaHashiRN, robert_kc and 47 others
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NicoleRaleigh
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Aug 25, 2025 at 6:26 AM#7

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Aug 25, 2025 at 7:26 AM
49 19MikeFit_NJ, InsuranceTom, WendyG_ATL and 46 others
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CarlaRPh_TPA
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Aug 25, 2025 at 7:38 AM#8
PharmD_Rodriguez said:
Small molecule does not automatically mean cheap.

Adding the part of the answer the thread has not reached. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Aug 25, 2025 at 11:38 AM
48 18BrianDallas92, labquiet_amy, emily_PDX and 45 others
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matt_MKE
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Aug 25, 2025 at 8:51 AM#9

A narrower follow-up, since the general answer is now clear:

What actually works on a prior-authorisation denial, as opposed to the list of things that sound like they should work?

Last edited: Aug 25, 2025 at 11:51 AM
47 17carl_compliance, DanielChem_CHI, marco_milano and 44 others
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VendorMark
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Aug 25, 2025 at 2:39 PM#10

Closing the loop on my own question.

Update: approved on the third attempt after a peer-to-peer. Nothing about my case changed; only who was doing the talking.

31 6claudia_zurich, nancy_portland, rick_sfbay and 28 others
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