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ForumsOral GLP-1 AgonistsATTAIN-2: orforglipron in T2DM — 12 month update Page 4

ATTAIN-2: orforglipron in T2DM — 12 month update

RetaRick_CA Sat, Aug 16, 2025 at 1:22 PM 35 replies 1,535 viewsPage 4 of 7
CarlaRPh_TPA
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Aug 23, 2025 at 2:28 PM#16

Clinical perspective, offered as context rather than as advice. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

30 5FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 27 others
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Dr.ObesityMed
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Aug 23, 2025 at 10:18 PM#17

Clinical perspective, offered as context rather than as advice. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

29 4PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 26 others
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bbq_ray_KC
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Aug 24, 2025 at 6:08 AM#18
Dr.ObesityMed said:
The version of this that has an answer is narrower than the version being asked.

Same experience, arrived at from the opposite direction.

28 3InsuranceTom, WendyG_ATL, SaraMom3 and 25 others
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Dr.CardioMD
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Aug 24, 2025 at 1:57 PM#19
Dr.ObesityMed said:
The version of this that has an answer is narrower than the version being asked.

Coming at Dr.ObesityMed’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Last edited: Aug 24, 2025 at 7:57 PM
27 2roxy_nash, tony_orlando, Dr.NephBHM_UK and 24 others
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Admin
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Aug 24, 2025 at 9:46 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.

5 5PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 2 others
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