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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral GLP-1 for elderly patients — anyone have experience? Page 3

Oral GLP-1 for elderly patients — anyone have experience?

EndoResFellow Sat, Jul 12, 2025 at 4:27 AM 45 replies 2,071 viewsPage 3 of 9
sarah.morrison
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Jul 15, 2025 at 3:14 AM#11
VanRx_Mike said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

That is the short version; the long version is somebody else's post.

34 7josh_phd_bmore, roxy_nash, tony_orlando and 31 others
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denise_HTX
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Jul 15, 2025 at 7:30 AM#12
MikeNYC_runner said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

This is exactly what I could not find anywhere else. I will report back once I have actually tried it.

35 8NeuroNate, JessicaH_TX, KevinCompounds and 32 others
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labquiet_amy
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Jul 15, 2025 at 11:46 AM#13
VanRx_Mike said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

I read this differently from VanRx_Mike, on substance rather than tone. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Last edited: Jul 15, 2025 at 1:46 PM
36 9LibrarianMeg, bri_stats, pete_manc_UK and 33 others
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dan_philly
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Jul 15, 2025 at 4:02 PM#14

Adding the numbers, since they settle part of this. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

37 10Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 34 others
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Admin
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Jul 15, 2025 at 8:18 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. No action needed from anybody.

Last edited: Jul 16, 2025 at 12:18 AM
38 11PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 35 others
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