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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHow far away are we really from an oral option — 12 month update Page 9

How far away are we really from an oral option — 12 month update

HPLC_Greg Wed, Jun 4, 2025 at 7:45 PM 47 replies 2,552 viewsPage 9 of 10
Dr.RheumBOS
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Jun 17, 2025 at 11:10 AM#41
raj_cambridge said:
If you are going to change something, change one thing and give it long enough to express itself.

This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.

15 13pam_stl, wei_SG, cory_ATX and 12 others
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Dr.CardioMD
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Jun 17, 2025 at 11:37 PM#42

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

Last edited: Jun 18, 2025 at 5:37 AM
16 14Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 13 others
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Admin
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Jun 18, 2025 at 12:04 PM#43

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Tagging this one for the weekly digest.

17 15RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 14 others
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TomTeleRx
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Jun 19, 2025 at 12:30 AM#44
Dr.CardioMD said:
It helps to ask what evidence would change your mind before you look at any.

Coming at Dr.CardioMD’s question from a different direction. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

18 16HPLC_Greg, LibrarianMeg, bri_stats and 15 others
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VendorMark
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Jun 19, 2025 at 12:56 PM#45

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

19 17claudia_zurich, nancy_portland, rick_sfbay and 16 others
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