DoseLogDan said:If you are going to change something, change one thing and give it long enough to express itself.
I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.
DoseLogDan said:If you are going to change something, change one thing and give it long enough to express itself.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
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View ResultsFrom the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
SarahChen_PharmD said:The mechanism and the magnitude are separate questions.
This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.