VanRx_Mike said:

If two explanations both fit, the useful question is which one predicts something the other does not.

That holds for the injectable. The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people quote them as if they were.

Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Ask again with the specifics and you will get a better answer than this one.

robert_kc said:

The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people…

Pushing back on robert_kc here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

Happy to go further on any of that.

robert_kc said:

The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people…

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

robert_kc said:

The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people…

Bookmarking. The distinction being drawn above is the one nobody else makes.

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.