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ForumsCompounding & FormulationPeptide oxidation and deamidation — storage condition impact Page 3

Peptide oxidation and deamidation — storage condition impact

PeptideChemSF Sat, May 16, 2026 at 4:40 PM 25 replies 816 viewsPage 3 of 5
oliver_london
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May 17, 2026 at 3:17 PM#11
Dr.RenalNash said:
Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…

This is exactly what I could not find anywhere else. Taking it to my next appointment.

Last edited: May 17, 2026 at 4:17 PM
5 3Admin, Dr.Martinez, mike_mod and 2 others
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rachel_ABQ
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May 17, 2026 at 8:35 PM#12

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

Happy to go further on any of that.

Last edited: May 18, 2026 at 1:35 AM
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BariatricNurseD
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May 18, 2026 at 1:54 AM#13
Dr.NutriCornell said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

I read this differently from Dr.NutriCornell, on substance rather than tone. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

7 5josh_phd_bmore, roxy_nash, tony_orlando and 4 others
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LabKate
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May 18, 2026 at 7:13 AM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: May 18, 2026 at 10:13 AM
8 6emily_PDX, Dr.SleepRoch, laura_annarbor and 5 others
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Admin
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May 18, 2026 at 12:32 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.

9 7PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 6 others
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