Dr.PathRoch said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.
SallyK_inj said:The mechanism is more central than most summaries suggest.
This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.
Dr.PathRoch said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
Ask again with the specifics and you will get a better answer than this one.
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Shop Reference StandardsOne concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.