VendorMark said:Dose-response modeling for tirzepatide: Emax model fitting to the STEP/SURMOUNT dose-finding data shows: Semaglutide: ED50 ≈ 0.6mg, Emax ≈ -18%, Hill…
This matches mine closely enough to be worth saying so out loud.
hank_denver said:Say what you would expect to see if you were wrong, before you look.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
hank_denver said:Say what you would expect to see if you were wrong, before you look.
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
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Browse GL Biochemhank_denver said:Say what you would expect to see if you were wrong, before you look.
Genuinely useful, thank you. I had the facts and not the framework. Sending this to two other people who asked me the same thing last week.