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ForumsOral GLP-1 AgonistsSmall molecule vs peptide GLP-1 agonists — what worked for you? Page 3

Small molecule vs peptide GLP-1 agonists — what worked for you?

claudia_zurich Tue, Jan 9, 2024 at 7:49 AM 20 replies 2,403 viewsPage 3 of 4
Dr.ObesityMed
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Jan 15, 2024 at 6:25 AM#11
sophie_paris said:
The useful move here is to separate what is established from what is widely repeated.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

26 1EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 23 others
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JenMemphis
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Jan 15, 2024 at 2:06 PM#12
Dr.NateNeph said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

That reframing is the part I needed.

Last edited: Jan 15, 2024 at 7:06 PM
25 0BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 22 others
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hans_munich
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Jan 15, 2024 at 9:47 PM#13
sophie_paris said:
The useful move here is to separate what is established from what is widely repeated.

Pushing back on sophie_paris here. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

24 24Dr.LipidDallas, alex_tucson, kevin_tulsa and 21 others
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HPLC_Greg
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Jan 16, 2024 at 5:28 AM#14

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

Last edited: Jan 16, 2024 at 11:28 AM
23 23Dr.MetabolicMD, RetaRick_CA, JenPlateau and 20 others
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Admin
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Jan 16, 2024 at 1:10 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

22 22PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 19 others
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