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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareThe "Ozempic face" phenomenon — 6 month update Page 5

The "Ozempic face" phenomenon — 6 month update

JakeBK_lifts Thu, Jul 3, 2025 at 3:48 AM 21 replies 1,506 viewsPage 5 of 5
TirzTom
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Jul 7, 2025 at 5:41 AM#21

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

11 9josh_phd_bmore, roxy_nash, tony_orlando and 8 others
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mike_nyc
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Jul 8, 2025 at 12:03 PM#22

A narrower follow-up, since the general answer is now clear:

How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?

Last edited: Jul 8, 2025 at 4:03 PM
12 10stefan_berlin, Dr.EM_Chicago, pete_RVA and 9 others
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Dr.BariatricHTX
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Jul 9, 2025 at 6:26 PM#23
TirzTom said:
Say what you would expect to see if you were wrong, before you look.

Pushing back on TirzTom here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

13 11Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 10 others
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ChrisMacros
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Jul 11, 2025 at 12:50 AM#24
TirzTom said:
Say what you would expect to see if you were wrong, before you look.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

14 12LibrarianMeg, bri_stats, pete_manc_UK and 11 others
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marco_milano
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Jul 12, 2025 at 7:15 AM#25
TirzTom said:
Say what you would expect to see if you were wrong, before you look.

Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.

15 13emma_london, tammy_FL, Dr.LipidDallas and 12 others
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