Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
PeptideSynthNJ said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
PeptideSynthNJ said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.
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Shop Reference StandardsFrom the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
If somebody has the primary source to hand I would rather cite it than paraphrase it.