Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

One thing that is still open after Dr.CardioMD’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

I would rather be corrected than agreed with, if it comes to it.

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

This answered a question I did not know how to ask. I will report back once I have actually tried it.