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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralTherapy + GLP-1 = the combination nobody talks about enough — 6 month update Page 3

Therapy + GLP-1 = the combination nobody talks about enough — 6 month update

Dr.AddMedPHL Sat, Oct 19, 2024 at 3:48 AM 37 replies 1,966 viewsPage 3 of 8
hannah_MT
New Member
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Feb 2026
Bozeman, MT
Oct 20, 2024 at 1:43 PM#11
Dr.SleepRoch said:
Mood changes on mental health: I want to be transparent — I went through a rough patch emotionally around month 3.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Adding it to my notes with a link back to this thread.

Last edited: Oct 20, 2024 at 4:43 PM
17 15nick_newbie, DadBodDave, AmyNC_wife and 14 others
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NurseLeah_Nash
Member
278
1,234
Sep 2024
Nashville, TN
Oct 21, 2024 at 1:03 PM#12

Adding the clinical framing, because it changes how the question reads.

When to call your doctor about mental health side effects — a reference I wish I'd had:

Call immediately:

  • Severe abdominal pain (could be pancreatitis)
  • Vision changes (thyroid concern)
  • Lump in neck (thyroid nodule)
  • Severe vomiting/can't keep fluids down for 24h+

Schedule an appointment:

  • Persistent nausea beyond 4 weeks
  • Significant hair loss
  • Mood changes or depression
  • Gallbladder symptoms (RUQ pain after eating)
18 16BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 15 others
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PharmD_Rodriguez
Senior Member
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14,567
Jan 2024
Miami, FL
Oct 22, 2024 at 12:22 PM#13
roxy_nash said:
Therapy insights from my mental health journey: my therapist introduced me to the concept of "identity updating" — the psychological work of becoming…

Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me. Change — even positive change — is stressful. I was anxious about loose skin.

This is more common than people admit. A therapist who specializes in weight management has been invaluable. Don't neglect the mental health side of this journey.

19 17robert_kc, dan_philly, MeganSA_TX and 16 others
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DanielChem_CHI
Senior Member
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5,678
Mar 2024
Chicago, IL
Oct 23, 2024 at 11:41 AM#14
Dr.AddMedPHL said:
The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Before/after narrative for mental health — one year in:

Before (292 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications, dreaded mirrors, avoided photos, social anxiety about my weight.

After (197 lbs): Run 3 miles regularly, pain-free, A1C normal, down to 1 medication, bought a swimsuit for the first time in a decade, actually enjoy being photographed.

Total weight lost: 77 lbs. Total life gained: immeasurable. This isn't just about weight — it's about reclaiming your identity.

20 18ben_calgary, patPC_UT, Dr.DermMIA and 17 others
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mike_mod
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Nov 2023
New York
Online
Oct 24, 2024 at 10:59 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

21 19PurityPaulOR, MaxMetOK, MounjBrad and 18 others
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