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ForumsCompounding & FormulationNeedle gauge and dead space — March 2026 Page 8

Needle gauge and dead space — March 2026

TirzTom Wed, Jun 4, 2025 at 6:46 PM 49 replies 2,557 viewsPage 8 of 10
Dr.PathRoch
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Jun 29, 2025 at 7:02 PM#36

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

That is the short version; the long version is somebody else's post.

37 12MikeFit_NJ, InsuranceTom, WendyG_ATL and 34 others
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ZaraB_AL
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Jul 1, 2025 at 3:38 AM#37
Dr.PathRoch said:
The mechanism and the magnitude are separate questions.

Adding a me-too, because a thread of one person's experience is not much use. I had assumed I was the exception until I read this.

36 11KevinCompounds, TirzTom, TrialTracker_MD and 33 others
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CanadaChris
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Toronto, CA
Jul 2, 2025 at 12:15 PM#38
Dr.PathRoch said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Jul 2, 2025 at 6:15 PM
35 10maya_sedona, stefan_berlin, Dr.EM_Chicago and 32 others
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BiostatsBrad
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Durham, NC
Jul 3, 2025 at 8:53 PM#39

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

34 9james_edin, FranDenver, Dr.BariatricHTX and 31 others
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PharmHunterJen
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Jul 5, 2025 at 5:32 AM#40

A narrower follow-up, since the general answer is now clear:

What would you measure differently if you were starting again?

12 12mike_mealprep, NicoleRaleigh, james_edin and 9 others
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