This gets cited here weekly, usually second-hand, so it is worth setting out what it does and does not establish.
Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.
Where I think it is weakest: the subgroup findings are the part I trust least — with enough subgroups something is always significant, and these were not all pre-registered.
What would genuinely help is knowing how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything. I have searched first, so if this is covered somewhere point me at it and I will read it.
Note on sourcing:
Figures above are from the primary publication rather than the press summary. If a number here disagrees with one you have, post yours and we will work out which of us is reading a secondary source.