dave_SLC said:

One practical note: write down what you did and when, before you need it.

Bookmarking. The distinction being drawn above is the one nobody else makes. Taking it to my next appointment.

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

sarah_TO said:

The mechanism and the magnitude are separate questions.

Same experience, arrived at from the opposite direction.

sarah_TO said:

The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.