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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareHas anyone dealt with glp-1 and fertility?

Has anyone dealt with glp-1 and fertility?

Dr.NutriCornell Thu, May 2, 2024 at 11:49 PM 9 replies 2,048 viewsPage 1 of 2
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Dr.NutriCornell
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May 2, 2024 at 11:49 PM#1

Not trying yet and would like to be within the year, which makes the washout question the one that matters most to me right now.

What I actually want to know is what the washout thinking is before trying to conceive, and why nobody mentions that fertility often increases as a side effect.

Happy to be told the question itself is wrong.

11 14emily_PDX, Dr.SleepRoch, laura_annarbor and 8 others
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Dr.MetabolicMD
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May 3, 2024 at 12:40 AM#2
Dr.NutriCornell said:
Not trying yet and would like to be within the year, which makes the washout question the one that matters most to me right now.
Dr.NutriCornell said:
...everyone should be on fertility and pregnancy...

I understand the enthusiasm, but "everyone" is too broad. Contraindications exist: personal/family history of MTC or MEN2, history of pancreatitis, pregnancy/breastfeeding, and certain GI conditions.

Beyond contraindications, clinical judgment matters. A 22-year-old with BMI 28 and no comorbidities has a different risk-benefit calculation than a 55-year-old with BMI 38 and metabolic syndrome.

Let's advocate for ACCESS without advocating for UNIVERSAL use. They're different things.

Last edited: May 3, 2024 at 2:40 AM
12 15PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 9 others
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dave_SLC
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Salt Lake City, UT
May 3, 2024 at 1:31 AM#3
Dr.MetabolicMD said:
Dr.NutriCornell said: ...everyone should be on fertility and pregnancy...

Dr.MetabolicMD has the substance of this right. The condition it depends on is worth stating. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

Last edited: May 3, 2024 at 5:31 AM
13 16james_edin, FranDenver, Dr.BariatricHTX and 10 others
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NurseAsh_DET
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Sep 2024
Detroit, MI
May 3, 2024 at 2:22 AM#4
Dr.NutriCornell said:
Not trying yet and would like to be within the year, which makes the washout question the one that matters most to me right now.

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

Last edited: May 3, 2024 at 8:22 AM
14 17labquiet_amy, emily_PDX, Dr.SleepRoch and 11 others
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roxy_nash
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Nashville, TN
May 3, 2024 at 7:09 AM#5

Clinical perspective, offered as context rather than as advice. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

15 18kim_atl_prep, sarah_TO, wendy_avl and 12 others
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