Dr.AddMedPHL said:

Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before.

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much worse. The combination of delayed gastric emptying + exercise-induced blood flow redistribution is rough on the GI system.

My workaround: inject Friday evening, do low-intensity activity Saturday, and save my intense workouts for Tuesday-Thursday when the GI effects have subsided. Timing your training around your injection schedule is a real optimization strategy.

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

HPLC_Greg said:

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much…

Coming at HPLC_Greg’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

One thing that is still open after tyler_CSCS’s answer:

Was that from a primary source or from a summary of one?

Closing the loop on my own question.

For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.