MASHdoc_SA said:

It is worth asking what the claim would look like if it were false.

Agreeing with MASHdoc_SA, and the qualification matters more than the agreement. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

Ask again with the specifics and you will get a better answer than this one.

Dr.BariatricHTX said:

True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of…

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

MASHdoc_SA said:

It is worth asking what the claim would look like if it were false.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.