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ForumsRetatrutide & Triple AgonistsRetatrutide and fatty liver — MASH resolution rates in Phase 2 Page 3

Retatrutide and fatty liver — MASH resolution rates in Phase 2

MASHdoc_SA Mon, May 11, 2026 at 6:13 PM 23 replies 534 viewsPage 3 of 5
SleepDoc_PDX
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May 12, 2026 at 10:03 PM#11
Dr.PeteFamMed said:
The glucagon component looks paradoxical and is not.

Saving this. It is the first explanation that did not require me to already understand it.

40 13pete_nash, hank_denver, carlos_SATX and 37 others
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paige_pharma
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May 13, 2026 at 8:09 PM#12

From the other side of the consultation, briefly. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Ask again with the specifics and you will get a better answer than this one.

Last edited: May 13, 2026 at 9:09 PM
41 14Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 38 others
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Dr.PainCLE
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May 14, 2026 at 6:13 PM#13
Dr.NutriCornell said:
The liver data is among the strongest non-weight findings in the class.

Pushing back on Dr.NutriCornell here. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

42 15oliver_london, tane_welly, Dr.PathRoch and 39 others
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Dr.NateNeph
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May 15, 2026 at 4:18 PM#14

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: May 15, 2026 at 6:18 PM
43 16B12Beth, RickReta_CO, PharmHunterJen and 40 others
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mike_mod
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May 16, 2026 at 2:21 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Tagging this one for the weekly digest.

44 17PurityPaulOR, MaxMetOK, MounjBrad and 41 others
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