Dr.EndoIndy said:Whether it is right for the case being asked about depends on a detail that has not been given.
Mine went the same way, slower.
Dr.EndoIndy said:Whether it is right for the case being asked about depends on a detail that has not been given.
Adding the part of the answer the thread has not reached. The pharmacokinetics explain nearly every practical question asked here. Albumin binding above 99% slows clearance enough to make weekly dosing possible; a terminal half-life near a week means four to five weeks to steady state and therefore a four-week titration interval; subcutaneous bioavailability around 89% means injection site barely matters. Those three facts answer most timing questions before they are asked.
Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.
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View ResultsOne thing that is still open after Dr.EndoIndy’s answer:
Which effects tachyphylax and which persist, because the answer explains why tolerability improves while the appetite effect keeps working?
bri_stats said:For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
I would rather be corrected than agreed with, if it comes to it.